The Bioscan, 2 (1) 055-056,2007
An International Quarterly Journal of Life Sciences
web site: www.thebioscan.in 
A SENSITIVE SPECTROPHOTOMETRIC DETERMINATION OF CENTBUCRIDINE
HYDROCHLORIDE IN BULK DRUG & PHARMACEUTICAL FORMULATIONS
V. V. PANDE, *S.A.POLSHETTIWAR, J. G. CHANDORKAR**,
V. V. CHOPADE***, A. R. TEKANDE***, N.M. GOWEKAR***
Maharashtra Institute of Pharmacy, Paud Road, Kothrud, Pune - 411 038 **Innovassynth Technologies Ltd. Khopoli- 410 203 ***Siddhant College of Pharmacy, Pune - 412 109 E-mail:vishalpande1376@gmail.com

KEY WORDS

Centbucridine
Spectrophotometric
Assay
Recovery



Received on: 11.10.2006

Accepted on: 07.01.2007



*Corresponding
 Author

ABSTRACT

A new, simple, sensitive Spectrophotometric method in ultravoilet region has been development for the determination of Centbucridine hydrocloride in bulk and in dosage from. Centbucridine Hydrocloride show maximum absorbance at 247nm with apparent molar absorptivity of 1.0781 X 104 l/mol.cm. Beer's law was obeyed in the concentration range of 5 to 50 ug/ml. Result of analysis wer validated statistically and by recovery studies. The development method was found to be sensitive, accurate, precise and reproducible and can be used for the routine quality control analysis of Centbucrine.