The Bioscan, 3(4): 409-412, 2008
An International Quarterly Journal of Life Sciences
web site: www.thebioscan.in 
EFFECT OF CHRONIC EXPOSURE OF SODIUM FLUORIDE ON ELECTROLYTE BALANCE OF 
GUPPY, POECILIA RETICULATA PETERS
HITESH U. SHINGADIA* AND VEENA SAKTHIVEL  
Department of Zoology, S. V. K. M’s Mithibai College,
J. V. P. D., Vile Parle (West), Mumbai - 400 056. Maharashtra, INDIA
E-mail: hiteshshingadia@yahoo.co.in

KEY WORDS
Calcium
Sodium
Potassium
Poecilia reticulata Received on: 23.05.2008 Accepted on: 17.11.2008 *Corresponding Author

ABSTRACT

The effect of sodium fluoride, a highly soluble salt of Fluorine on the electrolyte balance of the larvivorous fish Poecilia reticulata Peters commonly known as Guppy was studied. The fish were exposed to different sub lethal concentrations (5.75 ppm, 7.18 ppm and 9.58 ppm) of fluoride for the period of 30 days and 60 days respectively. The study revealed a significant decrease in the concentration of electrolytes (Na+, K+ and Ca+2) in the tissue of the treated fish when compared to the control at the end of the exposure period. Such an electrolyte imbalance could be caused due to chronic fluoride intoxication. The reduced Calcium content might result in decalcification of hard tissues of the fish. Hypocalcaemia, hyponatremia and hypokalemia observed in the present investigation indicates the derangement of electrolyte transport, which may be due to the change in permeable properties of the biomembrane systems to different extent by altering the Ca+2 pump or Na+ - K+ pump, rupture of epithelium, disturbance in mitochondrial integrity, disturbed adrenal and kidney function and/or subsequent respiratory distress.